June 4th live fpoty on tv


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The phone rang at 8am and I dashed over to answer it as my other half's dad has fallen recently and had to go into hospital 😔 and well he is frail and you think the worst re a relapse.☹Anyway turns out someone was phoning their Dr and it was a wrong number but by dashing I've pulled stuff and now there is a major protest going on 🙄

Morning missus. Hope you are ok and hope FIL recovers soon xx
 
Were fine thank you.
I get the holiday industry issue, but the public are propping them up through this.
Did contact the credit card company and they asked what l had been offered to which if they have offered a refund they would not at this point unless they renege on it.
They are still breaking the law, insurance sent an email saying if you have taken the policy out before 17th March you were covered, well they say if you been made an offer then they will not payout
Have a gud un
Regulations and T&C's are that if they cancel flights you are entitled to a full refund, AmEx agreed with me hence refunding me. I guess you will be covered one way or other but its a complete pfaff, and farce that you are out of pocket in meantime, if the travel company go down you can claim via credit card company, I would do it that way as insurance policy will probably have an excess so won't get full amount back that way.
 
Morning Hank, morning all.
Good morning BC

No indeed Mr D, he is a worry as he is mid 80's now and very frail. He fell in the bathroom, split his face open and was trapped. The ambulance people had to free him but obviously he was in shock and a great deal of pain and you do worry about that. 😶
Morning GS sorry to read that, best wishes to him and yourself

Just finished having a well earned coffee
You or the football. Enjoy the coffee marra

Morning Hank, morning everyone
NotPlsfm.
It looks as if it's going to rain so I'm off for my walk then back to watch the gee-gees.
Stay safe everyone👍
Good morning Bonzo lad
 
Morning Dilli...same old mate, a bit of relief during the day but it worsens as the day progresses...got an xray on 9th booked...its to determine weather my spine has collapsed...if it has then an operation should follow imminently....

Bit of a never ending nightmare to be honest Dilli marra...
Sounds a complete nightmare MK. Best of luck getting it sorted.
 
Daughter (no) started her text “Coming down today, don‘t tell Mam......” but it was a pointless exercise as I’d started reading it out loud.

So, Little Duckling and probably dog will be here shortly for a walk, talk and visit to Queen Mother (her Grandma and ducklings Great Grandma).

She must be keen as battery was flat and car had to be jump started.

Just filled/topped mine up since before lockdown £31, saving a fortune.
 
Morning Dilli...same old mate, a bit of relief during the day but it worsens as the day progresses...got an xray on 9th booked...its to determine weather my spine has collapsed...if it has then an operation should follow imminently....

Bit of a never ending nightmare to be honest Dilli marra...
A collapsed spine sounds horrific mate. Whilst I hope it’s not that, if it gets you the attention you obviously desperately need then...
anyway, I’m hoping that whatever it is they can get you fixed up soon.
enjoy your time with your daughter mate. I’ve got three of them, I see two of them regularly as they live not far away, but I haven’t seen my youngest since Xmas and I miss her very much. She’s up on the west coast of Scotland just now, hopefully when and if things ease up I’ll either go up there or she can come down here. I’m just annoyed when I see these big demonstrations and packed beaches, that the people involved don’t really give a shit and are making it worse for everyone. That and a spineless government that don’t have the balls to follow or properly enforce their own restrictions.
Or the minge?!
Also marra.
Daughter (no) started her text “Coming down today, don‘t tell Mam......” but it was a pointless exercise as I’d started reading it out loud.

So, Little Duckling and probably dog will be here shortly for a walk, talk and visit to Queen Mother (her Grandma and ducklings Great Grandma).

She must be keen as battery was flat and car had to be jump started.

Just filled/topped mine up since before lockdown £31, saving a fortune.
Good time to have a few 45 gallon drums stashed mate.
 
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Regulations and T&C's are that if they cancel flights you are entitled to a full refund, AmEx agreed with me hence refunding me. I guess you will be covered one way or other but its a complete pfaff, and farce that you are out of pocket in meantime, if the travel company go down you can claim via credit card company, I would do it that way as insurance policy will probably have an excess so won't get full amount back that way.
Your right mate, what it needed was a money person to have taken one company to court for care of duty.
I was told of a family who paid 15k for a holiday and still having to wait to be paid out. Scandalous.
Branson made his money from the public and now expect the public to bail the him out, he can bog off.
We have decided to stay at home now this year and see what happens as things unfold
 
Morning Dilli, I’m just back from Morrison’s. No queue hardly anyone in. More staff packing for click and collect than customers. Great.
Pleased to hear it mate. I’ve been a bit concerned about some of your earlier posts re social distancing or lack of. It seems some people just don’t or won’t get it. This thing hasn’t magically disappeared overnight as yesterday’s figures show. It’s nuts man.
Morning All,

Quiet at home as H & T are off to Luton for her mother's funeral. I'm staying safe at home. No rain around, but it's overcast. Today something truly silly:

Morning Grumps. 😂😂😂👍
 
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Pleased to hear it mate. I’ve been a bit concerned about some of your earlier posts re social distancing or lack of. It seems some people just don’t or won’t get it. This thing hasn’t magically disappeared overnight as yesterday’s figures show. It’s nuts man.

Morning Grumps.
SWMBO is fuming cos I didn’t stick to her list and added a few things mesel. She’s putting the shopping away right now and I can hear her stamping about and slamming cupboard doors. I usually do that with her but after her earfull she can get on with it. I’m waiting for her to start the second onslaught and will gently inform her that next week she can get the shopping hersel.😀
 
A collapsed spine sounds horrific mate. Whilst I hope it’s not that, if it gets you the attention you obviously desperately need then...
anyway, I’m hoping that whatever it is they can get you fixed up soon.
enjoy your time with your daughter mate. I’ve got three of them, I see two of them regularly as they live not far away, but I haven’t seen my youngest since Xmas and I miss her very much. She’s up on the west coast of Scotland just now, hopefully when and if things ease up I’ll either go up there or she can come down here. I’m just annoyed when I see these big demonstrations and packed beaches, that the people involved don’t really give a shit and are making it worse for everyone. That and a spineless government that don’t have the balls to follow or properly enforce their own restrictions.

Also marra.

Good time to have a few 45 gallon drums stashed mate.

Yup, biggest thing is impact of people/family etc, nightmare tbh

Beaches were closed & roads to them blocked off/policed. Gov ( Boris) altered that without any conversations with police/local authorities on the issues, impact etc & even all 4 of his “science “ colleagues didn’t want it

demonstrations are banned all the time, as these could have been

I’m coming to the conclusion the person who said the only reason to follow this path is to spread the virus whilst NHS could cope was correct

This is reinforced by the much talked about severity of a 2nd Spike that doesn’t exist in any country anywhere ffs

Anyways, I’m sat outside, just got out the f’ken kitchen since 8 o’clock 🙄. Cloudy as but the ☀️ sneaks out now & again & its git hot

....climbs down from soapbox 🙄🙄🙄😄👍
 
Your right mate, what it needed was a money person to have taken one company to court for care of duty.
I was told of a family who paid 15k for a holiday and still having to wait to be paid out. Scandalous.
Branson made his money from the public and now expect the public to bail the him out, he can bog off.
We have decided to stay at home now this year and see what happens as things unfold
Same Sis, won't be going anywhere this summer, had a big trip planned to celebrate eldest 18th and Mrs 50th but delayed that till next year and so don't have to pay balance till then, I wouldn't feel safe flying. Friends of Mrs have booked at 2 week holiday to Ibiza in July and no intention to delay it, I think they are mad.

I just hope things get clearer for eldest to go backpacking to NZ and Oz later in the year, otherwise he is going to have a pretty shitty gap year
 
Your right mate, what it needed was a money person to have taken one company to court for care of duty.
I was told of a family who paid 15k for a holiday and still having to wait to be paid out. Scandalous.
Branson made his money from the public and now expect the public to bail the him out, he can bog off.
We have decided to stay at home now this year and see what happens as things unfold
Branson's in a reet pickle, Sis, la. In the interests of fairness & balanced reporting, I should perhaps add that he's also an utter ****.
 
I thought I'd try to post this article as it might be of interest to some. I can hoy up the link without much problem, but I've switched from furn to PC in the hope of achieving a copy & paste, thereby circumventing the paywall (for reasons which elude me, I can't copy text from The Times online on my furn, but sometimes I can on my PC). Bear with me (which is a daft thing to say, because by the time you read this - if ye can be arsed to read it - I'll have done whatever I can or can't do & you'll have no perception of the intervening time lapse, burrav said it now, so there it is):


There is a simple question that the experts who study viruses do not always relish being asked. The question is this: what is it that makes one disease give you lasting immunity, while in another it is fleeting?

“That is complicated,” says Shane Crotty, from the La Jolla Institute for Immunology in California.

“That’s really difficult,” agrees Deenan Pillay, professor of virology at University College London. “You would have to speak to a geeky immunologist about that.”

Dan Davis is professor of immunology at Manchester University, author of The Beautiful Cure, a book about the immune system, and a fully accredited geeky immunologist. “This is a crucial frontier that is shortly going to be of paramount importance,” he begins rather more promisingly. And his answer? “The truth is, it’s a really important gap in our knowledge. It’s a little bit mysterious.”


There is no shame in this — scientists happily admit that sometimes they operate at the edge of knowledge. But it is, nevertheless, a shame. Because as Professor Davis suggests, this question, currently, is really rather important.

On it hangs trillions of pounds and tens of thousands, perhaps hundreds of thousands, perhaps even millions, of lives. If an antibody test shows you have had coronavirus, does that mean you are immune to coronavirus? And for how long?
HOW IMMUNITY HAPPENS
Late last year, almost certainly in China, a human experienced something that had previously happened to no human in the world. A submicroscopic mix of protein molecules entered his or her body, found a cell in the throat or nose and inserted some genetic material to hijack it. This material was a code, 30,000 letters long and those letters in that precise sequence had never been inside a human. They were the new coronavirus.
In response, this human did something commonplace that is also extraordinary. So long as he or she survived, this person, this Patient Zero, not only fought it off, but found a way to attack it uniquely now and probably also, in the future. In the process he or she gained the antibodies that today are being tested for around the world.
Here is the standard description of how that happened.

In the body are cells called B-cells. On the surface of each cell are thousands of identical turrets of protein. Each turret is seeking its match — another protein, floating in the body, that will slot perfectly on to it, locking on.
On every individual cell, these turrets are identical. But each cell is different. And there are a lot of them. When a new B cell is made, its genes are shuffled to produce a new turret with a slightly different shape. This process can make 10 billion different flavours of turret. Enough, in fact, that there is pretty much nothing that can enter your body, whether virus or bacteria, to which there will not be a B-cell that can lock to it. Eventually, your body will find a match to one part of the coronavirus.
The immune system, in its complexity, is often called elegant. This first step, though, is not an elegant solution. It is deeply inelegant. It is what hackers would call a brute force attack, the equivalent of trying every password combination until you alight on the right one. But it works. When the B-cell finds its match it is activated and starts replicating.
Some of the copies it makes become factories, churning out soluble versions of those turrets — which we call antibodies — that lock on to the coronavirus. Antibodies can neutralise the virus directly, by stopping it being able to get inside a cell. They also flag the virus and infected cells for destruction by other immune cells. Some of these antibody-producing cells become “memory” cells, ready to mount a new defence if needed again.
And so it is that you become immune. How long for depends on how long your body decides to keep those cells and antibodies circulating. Sometimes it decides they are worth a long-term investment, sometimes not.

Antibody tests explained
When describing the immune system, it is hard not to talk of armies and soldiers and battles. But the mundane truth is, it is about atoms and structures that mindlessly lock and interlock.Why, in this wholly deterministic process, do we not know what happens next? The truth is, it is just too complex to understand that way.“The immune system is incredibly complicated,” says Eleanor Riley, professor of immunology and infectious disease at Edinburgh University. “Because it’s so important to us, it cannot have a single point of failure. There are loads of ways the body can see a virus, think ‘I don’t like this virus’, and get rid of it.”There are many parts of a coronavirus that a turret can lock on to, and there are also many methods — not covered in this simplified explanation — to do it. She likens it to a pinball falling through a machine. “There is no single path to the bottom. Put in a coronavirus, and like the pinball we know it will end up at the bottom, with immunity. But for every person it will do it differently.”
http://**Non GDPR compliant third party tracking link removed**/2IzS8C4
When the ball lands there may be the flashing lights that mark a high score — long-term immunity. Or it may get diverted into the gutter of temporary immunity, leaving you reaching for coins to put in the slot, and preparing to do it all over again.
ROUTE TO LASTING IMMUNITY
Smallpox is the only disease that has ever been eradicated in humans. Towards the end of the 20th century, thanks to a vaccine, a virus that once killed a third of those infected, and infected two thirds of the population, disappeared from the planet. The benefits in terms of human suffering are incalculable.
There is also a comparatively small benefit to virology. Unlike with any other virus, we can be sure that since the 1970s no one has been re-exposed to it. For Shane Crotty, from the La Jolla Institute for Immunology, this was useful. He looked for antibodies in those who had been given the vaccine in the last wave. He found the antibodies were still there, as strong as ever.
“As far as we can tell, people have memory of smallpox for 40-plus years, and it didn’t really change between year five and year 40. Those cells are just circulating in people’s blood.” And yet, he adds, “We definitely know of other cases where we’ll have an immune response, and it’s essentially undetectable after three years.”
Worryingly, some of the most ephemeral immune responses, lasting just months, come from coronaviruses. Not the coronavirus that has gained viral celebrity in the truest sense of the term but from those that cause a sniffle rather than a pandemic, part of the cocktail of viruses we call the common cold.
Yet look at another coronavirus still — the one that caused the deadly Sars outbreak of 2002 — and not only are antibodies still circulating in people, but they may even offer some protection against the new pandemic.
So which category is this latest coronavirus, the superstar coronavirus, going to fall into? The best clue comes not in what the viruses look like but in what they do. Do they leave you reaching for a tissue? Or for a ventilator?
“This immune memory may work like any other memory,” says Alessandro Sette, from the La Jolla Institute. “In life, if it’s a very traumatic event, you tend to remember it more.” In this idea, Dr Riley says, “the body needs to say, ‘Eh-up, there’s something here I need to pay attention to’. If a virus causes little damage, if it gets into your nose but goes no further, there may just be a trivial response.”
Here, there is both good news and bad news for the coronavirus. For those worst affected the disease is severe enough that the likelihood is we will have a proportionate immune response — that the health care workers incapacitated by it this winter will not have to endure it next winter. But there is another corollary. Just this week we learnt that as many as 70 per cent of people barely get a symptom. Will they also have long-lived immunity? And does it matter if they don’t?
That depends, Dr Riley says. “Was it mild because they are not at risk? Or was it because they did not get much virus to start with? If the former, there’s no need to worry.” If the disease does not affect them, then it does not matter if their immunity fades. “If the latter, if it’s just because they got a glancing blow, then next time they might not be lucky.”

It's by a bloke carld Tom Whipple, the science editor in The Times. Here's the link for those w

 
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