Weight loss jabs

[Oily Oily Oily]

Downside - take too much by even a small amount . Shit yourself away .



Plus- I’m still eating 4 -5 times a day but it’s normal portions. No walking up during the night starving.

Craving for drink has totally gone, tonight’s the 1st night I’ve drank for over a month. Pint and a half and I’ve had enough, before I’d be chucking double figures down.


Better , just better mentally. No tiredness at 3pm and so on as blood sugars are not spiking. My body just seems well.



When I eat I feel content after a feasible portion, before just keep going.



I think it’s great stuff, go over 1mg and I find it’s a real problem with shits and forgetting to eat. 1mg for me is the sweet spot, hungry at meal times only




Problem I’ve found with all these products they are used by fat people who’s lazy . Don’t sort their diet out, get the 15k steps a day in , heavy weights and so on. Their diets continue to be wrong and they will rebound massively.
I was out with someone who’s on it who was trying to force fries down. Idiots

Did you start on 0.5mg or straight to 1mg? I’ve seen others say they microdose every few days as well and get better results. Guess it just depends on the person.

I’m fine with the drink craving side. I feel like I will just eat on a night out of Bordem. Fine during the day when working. Get to an evening and it’s like all hell breaks loose. Can be similar on a weekend if I’m not busy.

 

[GillytheGilf]

Did you start on 0.5mg or straight to 1mg? I’ve seen others say they microdose every few days as well and get better results. Guess it just depends on the person.

I’m fine with the drink craving side. I feel like I will just eat on a night out of Bordem. Fine during the day when working. Get to an evening and it’s like all hell breaks loose. Can be similar on a weekend if I’m not busy.

It’ll help with all that craving .

I started on 1mg, went upto 1.5mg for one week and back down . Too strong and gave me the shits .
I’d advise 0.5mg and ramp it up incredibly slowly to 1mg.

 

[Oily Oily Oily]

It’ll help with all that craving .

I started on 1mg, went upto 1.5mg for one week and back down . Too strong and gave me the shits .
I’d advise 0.5mg and ramp it up incredibly slowly to 1mg.

Does the pen allow you to ramp up slowly? I was worried it was 1mg per dose on the pen.

 

[Ambivalent Dave]

Does the pen allow you to ramp up slowly? I was worried it was 1mg per dose on the pen.

If it’s anything like the mounjaro one it’s divided into 10 (probably more) “clicks” up to the full dose so you can administer fractions of it

 

[CatRyan]

My sisters and a friend of mine went on the jabs... I think they can be a great tool and for sure they lost weight.

I was worried about my sisters especially as this was a while back in lockdown times and before these jabs became more mainstream. I am against medicating life most of the time. So not going to even try and mask that.

Many moons ago I was offered these jabs by the hospital and begged them to let me challenge my diagnosis with nutrition and exercise. The nurse turned a jaundiced eye on me but I made it work and never needed the meds but at the weekly clinic I did get to witness people in wheelchairs, a foot gone already, eating crisps.

I wanted to show my sisters the jabs were not the only option and probably not the best option. Also, no lie, the thought of my evil sister being thinner than me was the most powerful motivation. Not defending that but won't deny it.
I lost more weight, more healthily and it was far more sustainable.
They are both bigger than me now.

I went keto, I didn't get ill from it, I could eat and enjoy eating as much as I liked.

I think these jabs are really useful and of course if your weight is a health issue, absolutely use the jabs. No question.

I do think you need to approach your nutrition at the same time though. Really overhaul that.

Use the jabs, make the changes and you honestly won't need the jabs anymore.

 

[GillytheGilf]

Does the pen allow you to ramp up slowly? I was worried it was 1mg per dose on the pen.

No

1. Dose Conversion Table

• 0.20 mg = 3 clicks
• 0.40 mg = 6 clicks
• 0.60 mg = 9 clicks
• 0.80mg = 12 clicks
• 1.00 mg = 15 clicks
• 1.20 mg = 18 clicks
• 1.40 mg = 21 clicks
• 1.60 mg = 24 clicks
• 1.80 mg = 27 clicks
• 2.00 mg = 30 clicks
• 2.20 mg = 33 clicks
• 2.40 mg = 36 clicks
• 2.60 mg = 39 clicks
• 2.80 mg = 42 clicks
• 3.00 mg = 45 clicks
• 3.20 mg = 48 clicks
• 3.40 mg = 51 clicks
• 3.60 mg = 54 clicks
• 3.80 mg = 57 clicks
• 4.00 mg = 60 clicks (maximum)

 

[Zak's Dad]

Aye, but that can be said of the other ones? I might have misunderstood but I was lead to believe this was one people choose who were active lifters (weights not shirts).

All sounds very similar other than the quickened metabolism. That said, suppose quickening the calorie deficit might mean losing too much too fast.

The significant difference between retatrutide and Mounjaro is the 3rd agonist which specifically targets glucagon production.
It basically tells your body to dump the fat in and around the liver into the blood and the other 2 agonists get the body to burn that.

If it's passed to get a licence for human use it'll not just be an incredible weight loss drug - it'll be the only drug around that can actually treat fatty liver disease. People on the current clinical trials have apparently gone from "failing liver" to "normal liver function tests" in 6 months!

In the past people like these only hope would have been a liver transplant. My GP is absolutely desperate for it to be used as quickly as possible.
And yes, Eli Lilly are claiming it has a 35% metabolic advantage so burns calories.

The obvious caveat is that no one can actually sell you real retatrutide because it's not available yet, it has no licence, but there are labs making it based upon the info out there from Lily and selling it on the grey market.

So you've no guarantee of quality or efficacy, however as people on this thread appear to have done - you can research it and try to find a reputable supplier who shows independent test results on their website and decide if you want to take the risk for yourself.
It does appear as if there's a LOT of suppliers out there so you should be able to make an informed choice.

 

[Darlo1973]

so. end of week 4 on 5mg mounjaro.

The good...
Blood glucose control is f***ing superb. Had to drop a separate, aggressive med I take to ensure I don't have hypo's. I'm now sitting comfortably within the 'normal' range, over the moon about it.

The bad...
weeks 2 & 3 on 5mg were rough as fuck. inject on monday, peak effect weds/thurs. horrifically ill on both days and both weeks. puking, shits, and the god awful burps. All overnight, so, no sleep and rough as fuck. Was extremely close to wrapping it all in.

the better....
end of week 4. Figured out because of the gastric slowdown, I simply can't eat a larger meal within about 6 hours of going to bed. Gastric slowdown, and lying down is a bad combo, without gravity helping the digestion. Its obviously slower just after jab, so it was way worse. Swapped meals around this week, eating earlier and this week has been absolutely fine. Since starting 2 months ago, I'm down about a stone and a half (which is bit too fast, but I put that down to having what felt like f***ing dysentery the last two weeks) so, will hopefully even out. tbh, it can stop for all I care, because my glucose seems to be under control.


p.s. I've gone off one of my favourite types of beer. which pissed me off no end at the time.

I have been very fortunate with very few side effects but the one thing I have learned is not to have a big meal before going to bed.

 

[xmfd]

I’ve been doing a lot of reading online and considering a low dose of reta for the summer - I’m not a fat man, 190lbs at 5’11. - just interested in lowering body fat and increasing lean muscle for summer whilst already consistently training/eating clean. Could happily get down to 175 but if I could lose mainly fat that would be incredible.
Any advice

 

[Zak's Dad]

I’ve been doing a lot of reading online and considering a low dose of reta for the summer - I’m not a fat man, 190lbs at 5’11. - just interested in lowering body fat and increasing lean muscle for summer whilst already consistently training/eating clean. Could happily get down to 175 but if I could lose mainly fat that would be incredible.
Any advice

Try everything other avenue first.



@GillytheGilf has done this very thing you're asking about with admittedly fantastic results. But your starting point is so healthy that resistance training on top of what you're doing would probably retain your muscle mass?

As a further caveat I would tell you as someone who has used tirzepatide to completely turn around my life - honestly I would only ever recommend using these agonists as a last resort when you've exhausted every other avenue because we really don't know the full extent of their impact on the body.

That being said if you're prepared to do the background research (as he has) and source them as reputably as you can from counterfeiters and accept the risks?

They can have a phenomenal effect as part of a regime to alter all parts of your lifestyle.

(In the spirit of full disclosure I'm thinking of combining a very small dose of reta with my 1 year tirzepatide maintenance dose and resistance training to try to alter my body composition after losing 5 & 1/2 stone since August because because of lost muscle mass.)

 

[Ambivalent Dave]

Try everything other avenue first.



@GillytheGilf has done this very thing you're asking about with admittedly fantastic results. But your starting point is so healthy that resistance training on top of what you're doing would probably retain your muscle mass?

As a further caveat I would tell you as someone who has used tirzepatide to completely turn around my life - honestly I would only ever recommend using these agonists as a last resort when you've exhausted every other avenue because we really don't know the full extent of their impact on the body.

That being said if you're prepared to do the background research (as he has) and source them as reputably as you can from counterfeiters and accept the risks?

They can have a phenomenal effect as part of a regime to alter all parts of your lifestyle.

(In the spirit of full disclosure I'm thinking of combining a very small dose of reta with my 1 year tirzepatide maintenance dose and resistance training to try to alter my body composition after losing 5 & 1/2 stone since August because because of lost muscle mass.)

Out of interest what’s your maintenance dose? Granted I’m on it for different reasons - but 5mg long term seems drastic. The two peak days are pretty rough for me, and can get nowhere near a calorie deficit level, never mind calorie maintenance

 

[Zak's Dad]

Out of interest what’s your maintenance dose? Granted I’m on it for different reasons - but 5mg long term seems drastic. The two peak days are pretty rough for me, and can get nowhere near a calorie deficit level, never mind calorie maintenance

So.

I never went to 15mg because the rate of my weight loss was ridiculous - both my consultant and GP warned against it so I stayed at 10mg.

But I'm using 15mg pens, dosing at 10 and buying every 4 weeks.
So I have 4 stockpiled pens in the fridge for maintenance and will have 5 by the time I finish the current pen.

When I finish this pen I'm going to drop from 10 to 7.5 for 4 weeks, then 5 and take stock.

I envisage testing things out to hit a dose between 2.5, 3.75 and 5 - maybe by taking a smaller dose more frequently like every 5 days?

The stockpiled pens mean I've got a "free" years worth of short / micro dosing.

I've already lost 5 & 1/2 stone (28%) from 19st 06lb to 14st, it looks like I've got 6 more 10mg doses to get to 6 stone (30%).

So the crucial thing for me is I'm not planning on using maintenance to lose more weight - just to keep the noise at bay while I continue to embed the massive nutrition / lifestyle changes / exercise as the new "normal".

(according to the clinical studies stay on a low dose for 1 year post treatment makes a massive difference to successfully keeping it off)

The second thing to remember is that after about 6 months your body starts to accommodate the medication and the side effects (and efficacy) wear off.

Out of interest what’s your maintenance dose? Granted I’m on it for different reasons - but 5mg long term seems drastic. The two peak days are pretty rough for me, and can get nowhere near a calorie deficit level, never mind calorie maintenance

A much shorter answer is "drop down and even experiment with longer dosing than 7 days".

If you're still in deficit and the bloods are great then whatever works - but especially as you're on prescription and not buying privately - speak to your doctor about ANY changes you make or want to make - they should be able to answer these questions much better.

 

[Ambivalent Dave]

So.

I never went to 15mg because the rate of my weight loss was ridiculous - both my consultant and GP warned against it so I stayed at 10mg.

But I'm using 15mg pens, dosing at 10 and buying every 4 weeks.
So I have 4 stockpiled pens in the fridge for maintenance and will have 5 by the time I finish the current pen.

When I finish this pen I'm going to drop from 10 to 7.5 for 4 weeks, then 5 and take stock.

I envisage testing things out to hit a dose between 2.5, 3.75 and 5 - maybe by taking a smaller dose more frequently like every 5 days?

The stockpiled pens mean I've got a "free" years worth of short / micro dosing.

I've already lost 5 & 1/2 stone (28%) from 19st 06lb to 14st, it looks like I've got 6 more 10mg doses to get to 6 stone (30%).

So the crucial thing for me is I'm not planning on using maintenance to lose more weight - just to keep the noise at bay while I continue to embed the massive nutrition / lifestyle changes / exercise as the new "normal".

(according to the clinical studies stay on a low dose for 1 year post treatment makes a massive difference to successfully keeping it off)

The second thing to remember is that after about 6 months your body starts to accommodate the medication and the side effects (and efficacy) wear off.


A much shorter answer is "drop down and even experiment with longer dosing than 7 days".

If you're still in deficit and the bloods are great then whatever works - but especially as you're on prescription and not buying privately - speak to your doctor about ANY changes you make or want to make - they should be able to answer these questions much better.

Aye. I’m thinking about 2.5 will be me long term. My diabetic nurse is class, and lets me lead on it, provided the numbers back it up. I reckon another month or two on 5mg to sort this last stone out. Will be going for a hba1c (longer term blood glucose test) in the next 3 weeks or so, and go from there

 

[Zak's Dad]

Aye. I’m thinking about 2.5 will be me long term. My diabetic nurse is class, and lets me lead on it, provided the numbers back it up. I reckon another month or two on 5mg to sort this last stone out. Will be going for a hba1c (longer term blood glucose test) in the next 3 weeks or so, and go from there

An interesting thing for me was because I wasn't getting NHS guidance, the pharmacy doctors were basically screaming at me to keep increasing the dose.

When I thought "whoa, this rate of weight loss is too much" I went to the GP and consultant who both told me to not dose higher and that medication should always be "lowest effective clinical dose".

Sounds like you're get much more measured advice than "spend more money! Lose weight even faster!"



I'm hoping to use 2.5 as a maintenance dose too but come off completely next year.

Good luck with the glucose test and update the thread if you fancy it. If its worked for you like this so far I can't see why 2.5mg won't be good maintenance dose to play with by dosing short or longer than 7 days.
(Tirzepatide is actually a medication with a 5 day half life anyway, Lily just set the dose regime at 7 days to make it easy for people to remember!)

 

[Whitburnmakem]

It’ll help with all that craving .

I started on 1mg, went upto 1.5mg for one week and back down . Too strong and gave me the shits .
I’d advise 0.5mg and ramp it up incredibly slowly to 1mg.

I can get the pens for £180 off my dietician now like gilly think the 50 mg so should last ages.

Been using wegovy for now as cheaper only on 0.5 and I’m not even trying now and lot another 2lbs this week, had an Indians 2 bottles of wine and about 12 cans of cruzcampo last weekend anarl I’m 13.6 now down from 15.8.
Starting to resemble Brad pit in fight club

No

1. Dose Conversion Table

• 0.20 mg = 3 clicks
• 0.40 mg = 6 clicks
• 0.60 mg = 9 clicks
• 0.80mg = 12 clicks
• 1.00 mg = 15 clicks
• 1.20 mg = 18 clicks
• 1.40 mg = 21 clicks
• 1.60 mg = 24 clicks
• 1.80 mg = 27 clicks
• 2.00 mg = 30 clicks
• 2.20 mg = 33 clicks
• 2.40 mg = 36 clicks
• 2.60 mg = 39 clicks
• 2.80 mg = 42 clicks
• 3.00 mg = 45 clicks
• 3.20 mg = 48 clicks
• 3.40 mg = 51 clicks
• 3.60 mg = 54 clicks
• 3.80 mg = 57 clicks
• 4.00 mg = 60 clicks (maximum)

Depends on the pen tho surely all different manufacturers and styles

 

[GillytheGilf]

I can get the pens for £180 off my dietician now like gilly think the 50 mg so should last ages.

Been using wegovy for now as cheaper only on 0.5 and I’m not even trying now and lot another 2lbs this week, had an Indians 2 bottles of wine and about 12 cans of cruzcampo last weekend anarl I’m 13.6 now down from 15.8.
Starting to resemble Brad pit in fight club

Depends on the pen tho surely all different manufacturers and styles

1mg a week works for me personally. Hungry at the right times and removes the urge to eat shite

 

[Whitburnmakem]

1mg a week works for me personally. Hungry at the right times and removes the urge to eat shite

I’m still on the wegovy atm like maybe try reta in future

 

[Darlo1973]

Sticking at 12.5mg Mounjaro for now as I feel it's enough for me. Going to give it another 2-3 months then consider scaling down the doses to see how I get on. Another stone before the summer holidays would be good.

 

[Zak's Dad]

Sticking at 12.5mg Mounjaro for now as I feel it's enough for me. Going to give it another 2-3 months then consider scaling down the doses to see how I get on. Another stone before the summer holidays would be good.

How much will that be in total and percentage wise mate?

I thought you'd already shifted a load?!

 

[GillytheGilf]

One thing I must hammer home is nutrition, walking and especially weights.


You need to sort all these out before you start th jabs. Weights is an absolute must