M56 - that's way I would normally go but the M6 is the much better option at the moment, as there're 3 massive sets of roadworks with 50mph limits on the M62 in Leeds/Huddersfield areas, which cause long delays.
Also avoids going around the Manchester M60 orbital which can be very slow at certain times of the day
I would go A66/M6. About 10 miles further but fast open road all the way and you avoid Leeds and Manchester. A1(M) is a proper shitefest in North Yorks.